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This article is about the cellular structure. For other uses, see Spindle (disambiguation).

In cell biology, spindle apparatus refers to the subcellular structure of eukaryotic cells that segregates chromosomes between daughter cells during cell division. It is also referred to as the mitotic spindle during mitosis, a process that produces genetically identical daughter cells, or the meiotic spindle during meiosis, a process that produces gametes with ½ the number of chromosomes of the parent cell.

Besides chromosomes, the spindle apparatus is composed of hundreds of proteins. Microtubules comprise the most abundant components of the machinery.

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