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Sex differences in humans have been studied in a variety of fields.
In humans, biological sex is determined by five factors present at birth: the presence or absence of a Y chromosome, the type of gonads, the sex hormones, the internal reproductive anatomy (such as the uterus in females), and the external genitalia. People with mixed sex factors are intersexed. People whose internal experience differ from their biological sex are transgendered or transsexual. A distinction is sometimes made between sex and gender. Sex differences in physical sciences tend to refer solely to people according to their biological sex, regardless of the person's self-perceived gender. Sex differences in other fields, such as when studying social roles, may use the person's gender, regardless of whether the person is intersexed or biologically the other sex.
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