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For a more general introduction to the topic, see Introduction to quantum mechanics.

In quantum mechanics, the Schrödinger equation is a partial differential equation that describes how the quantum state of a physical system changes with time. It was formulated in late 1925, and published in 1926, by the Austrian physicist Erwin Schrödinger.

In classical mechanics, the equation of motion is Newton's second law, (F = ma), used to mathematically predict what the system will do at any time after the initial conditions of the system. In quantum mechanics, the analogue of Newton's law is Schrödinger's equation for a quantum system (usually atoms, molecules, and subatomic particles whether free, bound, or localized). It is not a simple algebraic equation, but in general a linear partial differential equation, describing the time-evolution of the system's wave function (also called a "state function").

The concept of a wavefunction is a fundamental postulate of quantum mechanics. Schrödinger's equation is also often presented as a separate postulate, but some authors assert it can be derived from symmetry principles. Generally, "derivations" of the Schrödinger equation demonstrate its mathematical plausibility for describing wave–particle duality.

In the standard interpretation of quantum mechanics, the wave function is the most complete description that can be given of a physical system. Solutions to Schrödinger's equation describe not only molecular, atomic, and subatomic systems, but also macroscopic systems, possibly even the whole universe. The Schrödinger equation, in its most general form, is consistent with both classical mechanics and special relativity, but the original formulation by Schrödinger himself was non-relativistic.

The Schrödinger equation is not the only way to make predictions in quantum mechanics - other formulations can be used, such as Werner Heisenberg's matrix mechanics, and Richard Feynman's path integral formulation.

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