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Hirsuties coronae glandis (also known as "hirsutoid papillomas" and "pearly penile papules") are small protuberances that may form on the ridge of the glans of the human penis. They are a harmless anatomical variation. Though sometimes confused with HPV infection, the papules are not a sexually transmitted infection and are not contagious.

The papules appear as one or several rows of small, pearly or flesh-colored, smooth, dome-topped bumps situated circumferentially around the corona or sulcus of the glans. They may range in size from less than 1 mm to 3 mm. As of 1999, different studies have produced estimates of incidence ranging from 8 to 48 percent of all men. Studies suggest that it occurs more often on younger men and those who have not been circumcised. They are found in 33.3% of uncircumcised males, and 7.1% of circumcised males.

Hirsuties coronae glandis are sometimes described as vestigial remnants of penile spines, sensitive features found in the same location in other primates. In species which retain the full expression of penile spines, the spines contribute to sexual pleasure and quicker orgasms.

A similar expression, vestibular papillomatosis of the vulva or "hirsuties papillaris vulvae", occurs in females and similarly can be misinterpreted as an outbreak of the HPV infection. Like hirsuties papillaris genitalis, it is a normal variation on human anatomy.


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